E2P2 specifications


Unique identifier OMICS_24886
Name E2P2
Software type Pipeline/Workflow
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Computer skills Advanced
Version 3.1
Stability Stable
Maintained Yes


No version available



  • person_outline Seung Yon Rhee

E2P2 citations


The quality of metabolic pathway resources depends on initial enzymatic function assignments: a case for maize

BMC Syst Biol
PMCID: 5129634
PMID: 27899149
DOI: 10.1186/s12918-016-0369-x

[…] effect of the initial enzymatic function assignment pipeline on the final metabolic pathway resource.CornCyc 4.0 (http://www.plantcyc.org) was developed using the Ensemble Enzyme Prediction Pipeline (E2P2 v2.0) [] created by Plant Metabolic Network (PMN) [] in collaboration with MaizeGDB (http://www.maizegdb.org) [, ]. MaizeCyc 2.2 [] was developed based on the Ensembl XRef pipeline [, ] in collab […]


Multiscale Metabolic Modeling of C4 Plants: Connecting Nonlinear Genome Scale Models to Leaf Scale Metabolism in Developing Maize Leaves

PLoS One
PMCID: 4807923
PMID: 26990967
DOI: 10.1371/journal.pone.0151722

[…] model, which has several advantages:Gene associations The gene associations included in iEB5204 are those presented in CornCyc [], which are generated by the PMN Ensemble Enzyme Prediction Pipeline (E2P2) [], a homology-based protein sequence annotation algorithm trained on a reference dataset of experimentally validated enzyme sequences. The E2P2 approach is more comprehensive and scalable than […]

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