|Application:||miRNA array analysis|
|Number of samples:||8|
|Release date:||Mar 18 2016|
|Last update date:||Feb 10 2017|
|Diseases:||Melanoma, Neoplasms, Skin Neoplasms|
|Dataset link||miR-146a Exerts Differential Effects on Melanoma Growth and Metastatization.|
To identify microRNAs involved in malignant melanoma progression, miR profilings have been performed in our lab taking advantage of a human melanoma cellular model consisting of a poorly aggressive B-RAF V600E-mutated parental cell line (A375P) and its four variants MA-1, MC-1, MA-2 and MC-2, derived from one (MA-1 and MC-1) or two (MA-2 and MC-2) subsequent rounds of injections in mice and showing progressively increased metastatic potential.
Cristiano De Pitta