|Number of samples:||6|
|Release date:||Aug 23 2017|
|Last update date:||Nov 30 2018|
|Dataset link||The transcription factor Tcf1 ensures the development and cytotoxic function of NK cells by limiting the expression of Granzymes [ChIP-Seq]|
Splenic NK cells from Tcf7+/+ and Tcf7-/- mice were cultured with IL-2 for five days, and chromatin-immunoprecipitation (ChIP) was performed using antibodies against Tcf1 and the active epigenetic mark H3K4me3. DNA from these ChIPs was purified, amplified, and sequenced as single-end 100 base reads.