Dataset features

Specifications


Application: ChIP-seq analysis
Number of samples: 6
Release date: Aug 23 2017
Last update date: Nov 30 2018
Access: Public
Dataset link The transcription factor Tcf1 ensures the development and cytotoxic function of NK cells by limiting the expression of Granzymes [ChIP-Seq]

Experimental Protocol


Splenic NK cells from Tcf7+/+ and Tcf7-/- mice were cultured with IL-2 for five days, and chromatin-immunoprecipitation (ChIP) was performed using antibodies against Tcf1 and the active epigenetic mark H3K4me3. DNA from these ChIPs was purified, amplified, and sequenced as single-end 100 base reads.

Repositories


GEO

GSE92710

ENA

SRP095469

BioProject

PRJNA358408

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Contact


Paolo Angelino