Computational protocol: Rapamycin alleviates inflammation and muscle weakness, while altering the Treg/Th17 balance in a rat model of myasthenia gravis

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Protocol publication

[…] To confirm that the experimental analysis was appropriately powered, G*Power [,] was used to calculate the sample size. Given error probability as 0.05 (two-tailed), power as 0.95, and effect size as 0.60, sample size per experimental group was calculated as 25. Data analysis was conducted using SPSS17.0 statistical software (SPSS, Chicago, IL, U.S.A.). The intergroup positive rates are expressed as percentages and the intergroup differences were tested by χ2 tests and Fisher exact tests. In addition, two-tailed t tests were used for comparisons between continuous variables. P<0.05 was considered statistically significant. […]

Pipeline specifications

Software tools G*Power, SPSS
Application Miscellaneous
Organisms Rattus norvegicus
Diseases Autoimmune Diseases, Myasthenia Gravis, Xanthomatosis, Cerebrotendinous
Chemicals Cyclophosphamide, Sirolimus