Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 18
Release date: Nov 20 2018
Last update date: Nov 20 2018
Access: Public
Chemicals: Tunicamycin
Taxon: Candida albicans, Homo sapiens, Mus musculus
Dataset link Genome-wide expression profiling of Candida albicans transcription factor Crz2p

Experimental Protocol


Two-condition experiments: 1) Samples 1-6: Untreated (-Dox, Cy3-labeled) and Dox-treated (+Dox, Cy5-labeled, 40 µg/mL) during 2h and 4h in Yest Peptone Dextrose medium, 30ºC, 3 biological replicates for each time-point; 2) Samples 7-12: Comparison of a Candida albicans wild-type strain (Cy3-labeled) to a crz2-/- mutant (Cy5-labeled) grown under normoxia at 30ºC (standard lab growth conditions, Samples 7-9) or under hypoxia at 37ºC (BBL GasPak anaerobic jar in an incubator at 37ºC, Samples 10-12); 3) Samples 13-18: Comparison of Normoxia 30ºC-grown (Norm30C, Cy3-labeled) wild-type or crz2-/- mutant strains to hypoxia 37ºC-grown (Hyp37C, Cy5-labeled) wild-type (Samples 13-15) or crz2-/- mutant (Samples 16-18) strains, respectively.

Repositories


GEO

GSE67226

BioProject

PRJNA279298

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Contact


Sadri ZNAIDI