Dataset features

Specifications


Dataset type: Expression profiling by array, Transcriptome or Gene expression
Number of samples: 13
Release date: Jul 27 2017
Last update date: Jan 24 2018
Access: Public
Diseases: Neoplasms, Melanoma, Colorectal Neoplasms
Dataset link A ‘Synthetic-Sickness’ Screen for Senescence Re-engagement Targets in Mutant Cancer Backgrounds

Experimental Protocol


HCT116 colorectal cancer cells with heterozygous KRAS mutation and KRAS+/- cells in which the mutation is knocked out were reverse transfected with 50nM siRNA against ECT2 or scrambled control. 5 days post transfection, cells were harvested for RNA extraction.

Repositories


GEO

GSE100459

BioProject

PRJNA391892

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Contact


W. Nicol Keith