Dataset features

Specifications


Application: BS-seq analysis
Number of samples: 6
Release date: Aug 17 2016
Last update date: Sep 12 2018
Access: Public
Diseases: Tendinopathy
Dataset link Genome-wide alterations in DNA methylation identify Leprel2, Foxf1, Mmp25, Igfbp6 and Peg12 as disease-associated genes in murine Achilles tendinopathy

Experimental Protocol


Chronic Achilles tendinopathy was induced in WT C57/Bl6 male mice via two injections of TGF-β1 directly into the body of the tendon. Methylome analysis was conducted on the tendon DNA for the acute (3 day) response as well as the chronic response (14 and 28 days) under normal cage activity or with treadmill running and compared to un-injured mice.

Repositories


GEO

GSE80396

ENA

SRP073454

BioProject

PRJNA318791

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Contact


Katie Trella