Dataset features

Specifications


Application: DNA methylation array analysis
Number of samples: 3
Release date: Apr 17 2009
Last update date: Mar 21 2012
Access: Public
Diseases: Neoplasms, Ovarian Neoplasms
Chemicals: Cisplatin, Platinum, Carboplatin
Dataset link Promoter CpG island methylation data from A2780 (cisplatin-sensitive) and Round5 A2780 (cisplatin-resistant) cell lines.

Experimental Protocol


We treated clonally derived, drug-sensitive A2780 epithelial ovarian cancer cells with increasing concentrations of cisplatin. After several cycles of drug selection, the isogenic drug-sensitive and -resistant pairs were subjected to global CGI methylation analyses by differential methylation hybridization (DMH) using a customed 44K promoter CGI microarray.

Repositories


GEO

GSE15373

ArrayExpress

E-GEOD-15373

BioProject

PRJNA122939

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Contact


Meng Li

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