Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 20
Release date: Dec 16 2015
Last update date: Dec 16 2015
Access: Public
Diseases: Esophagitis, Gastroesophageal Reflux, Rat-Bite Fever
Chemicals: Omeprazole
Dataset link Beyond acid suppression: Novel therapeutic targets for gastro-esophageal reflux disease based on a murine model (whole blood)

Experimental Protocol


Refluxesophagitis was surgically induced. Wistar rats were pretreated for 7 days with omeprazole or STW5. Treatment was continued for 10days after surgery, rats were sacrificed and esophagi exiced. The study had 5 groups. Group 1: sham operated, Group 2: esophagitis group, untreated, Group3: esophagitis treated with STW5 0.5ml/kg. Group 4: esophagitis treated with STW5 2ml/kg. Group 5: esophagitis treated with Omeprazole (30mg/kg). 4 microarrays from esophageal tissue and blood from 4 animals of each group were performed.

Repositories


GEO

GSE63402

ArrayExpress

E-GEOD-63402

BioProject

PRJNA267667

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