|Application:||Gene expression microarray analysis|
|Number of samples:||20|
|Release date:||Dec 16 2015|
|Last update date:||Dec 16 2015|
|Diseases:||Esophagitis, Gastroesophageal Reflux, Rat-Bite Fever|
|Dataset link||Beyond acid suppression: Novel therapeutic targets for gastro-esophageal reflux disease based on a murine model (whole blood)|
Refluxesophagitis was surgically induced. Wistar rats were pretreated for 7 days with omeprazole or STW5. Treatment was continued for 10days after surgery, rats were sacrificed and esophagi exiced. The study had 5 groups. Group 1: sham operated, Group 2: esophagitis group, untreated, Group3: esophagitis treated with STW5 0.5ml/kg. Group 4: esophagitis treated with STW5 2ml/kg. Group 5: esophagitis treated with Omeprazole (30mg/kg). 4 microarrays from esophageal tissue and blood from 4 animals of each group were performed.