Computational protocol: Acellular Dermal Matrix Versus Inferior Deepithelialized Flap Breast Reconstruction: Equivalent Outcomes, with Increased Cost

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Protocol publication

[…] A retrospective, single-institution study was performed between July 1, 2012, and June 30, 2014, examining all immediate expander BRs using ADM or IDF. Included were all patients who underwent an acellular dermis or IDF immediate PMBR, with or without radiotherapy treatment. Patients who were younger than 18 years of age were excluded. All the patients underwent immediate PMBR with tissue expanders and none with immediate implant-based reconstruction.Abstracted data included demographics [age, body mass index (BMI), grade of ptosis), potential risk factors for postoperative morbidity (history of tobacco use, diabetes, pre-BR radiation therapy), and operative characteristics (type of operative procedure, laterality, duration, cost).Primary outcomes were categorized into 2 groups: clinical and aesthetic. Clinical complications requiring surgical intervention postoperatively included hematoma, seroma, partial flap necrosis, tissue expander leakage/exposure, and inframammary fold displacement. Aesthetic outcomes were measured by 5 different variables that included BR volume, contour, placement, scarring, and inframammary fold appearance as described by Nguyen et al. The scale described was a 3-point scale with ratings from 0 to 2 with higher scores being more favorable (Table ). Postoperative photographic data were scored by 2 blinded senior-level general surgery residents after being given explicit examples and instructions using the 3-point scale. None of the reviewers were involved with patient care.Statistical analysis was performed using the student’s t test for normally distributed continuous variables, Mann-Whitney U test for nonnormally distributed continuous data, and Fisher’s exact test for categorical data. Statistical significance level was set at α = 0.05. SPSS 18 for Windows (IBM, Armonk, N.Y.) was used to perform analyses. Institutional review board approval was granted. […]

Pipeline specifications

Software tools EXPANDER, SPSS
Application Miscellaneous
Organisms Homo sapiens
Diseases Breast Neoplasms