Computational protocol: The Insertion/Deletion Polymorphism of Angiotensin I Converting Enzyme Gene is Associated With Ossification of the Posterior Longitudinal Ligament in the Korean Population

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Protocol publication

[…] A statistical analysis was performed using the SPSS software (SPSS Inc., Chicago, IL, USA). The chi-square (χ2) test was used to value Hardy-Weinberg equilibrium. A logistic regression analysis controlling age and sex as co-variables in three models (codominant, dominant, and recessive model) was performed using SNPAnalyzer (ISTECH Inc., Goyang, Korea), Helixtree (Golden Helix Inc., Bozeman, MT, USA), and SNPstats (http://bioinfo.iconcologia.net/index.php) [,]. A p-value less than 0.05 was considered as statistically significant. […]

Pipeline specifications

Software tools HelixTree, snpStats
Application GWAS
Organisms Homo sapiens