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EADB specifications

Information


Unique identifier OMICS_18853
Name EADB
Alternative name Estrogenic Activity Database
Restrictions to use None
Community driven No
Data access File download
User data submission Not allowed
Maintained Yes

Maintainer


  • person_outline Huixiao Hong

Publication for Estrogenic Activity Database

EADB citation

library_books

CERAPP: Collaborative Estrogen Receptor Activity Prediction Project

2016
Environ Health Perspect
PMCID: 4937869
PMID: 26908244
DOI: 10.1289/ehp.1510267

[…] used by participants to train models:HTS data from Tox21 project consisting of ~ 8,000 chemicals evaluated in four assays (; ; ; ; ), extending beyond the 1,677 used in the training set.The U.S. FDA Estrogenic Activity Database (EADB), which consists of literature derived ER data for ~ 8,000 chemicals ().Estrogenic data for ~ 2,000 chemicals from the METI (Ministry of Economy, Trade and Industry, […]


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EADB institution(s)
Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, USA; School of Materials Science and Engineering, Chang’an University, Nan Er Huan Zhong Duan, Xi’an City, China; Office of Scientific Coordination, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, USA; National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA; Division of Reproductive and Urological Products and Division of Drug Safety Research, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA; Division of Food Contact Notifications, Office of Food Additive Safety, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, College Park, MD, USA; Division of National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, MD, USA; Office of the Texas State Chemist and Veterinary Pathobiology, Texas A&M University, College Station, TX, USA; Office of New Drugs and Division of Nonprescription Clinical Evaluation, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD, USA
EADB funding source(s)
Supported by Research Participation Program at the National Center for Toxicological Research administered by the Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and the U.S. Food and Drug Administration.

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