Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 22
Release date: Jan 1 2012
Last update date: Jul 26 2018
Access: Public
Diseases: Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Neoplasms
Chemicals: Amino Acids, Aspartic Acid, Cysteine
Dataset link Substitutions in the KRas oncogene determine protein behavior: Implications for signaling and clinical outcome.

Experimental Protocol


Gene expression profiles were measured in 22 core biopsies from patients with refractory non-small cell lung cancer included in the Biomarker-integrated Approaches of Targeted Therapy for Lung Cancer Elimination (BATTLE). All tumors were KRAS mutants, but with different patterns of amino acid substitutions. Supervised analysis of transcriptome profiling was performed to compare cysteine or valine KRAS mutants with other KRAS mutants.

Repositories


GEO

GSE27389

ArrayExpress

E-GEOD-27389

BioProject

PRJNA153915

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Contact


Pierre Saintigny