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ECgene specifications


Unique identifier OMICS_01884
Name ECgene
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained No


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Publication for ECgene

ECgene citations


ECGene: A Literature‐Based Knowledgebase of Endometrial Cancer Genes

Hum Mutat
PMCID: 5066700
PMID: 26699919
DOI: 10.1002/humu.22950

[…] Based on a systematic survey of EC‐related genes in public resources and literature, we have developed a user‐friendly Web interface to access all annotated information. Data and information in ECGene are stored in a MySQL relational database on a Linux server. Web‐based queries to the database are implemented in Perl scripts running in an Apache environment. ECGene allows users to quickly q […]


Associations of Haplotypes Upstream of IRS1 with Insulin Resistance, Type 2 Diabetes, Dyslipidemia, Preclinical Atherosclerosis, and Skeletal Muscle LOC646736 mRNA Levels

PMCID: 4451528
PMID: 26090471
DOI: 10.1155/2015/405371

[…] were used in univariate logistic regression analysis. Adjustments were made by including covariates in a second set of multivariate logistic regression models. The THESIAS program ( was used for testing associations between haplotypes and phenotypes. Covariate-adjusted haplotype-phenotype parameters, expressed as OR for binary phenotypes or average effects for continu […]


The Evolution of Fungal Metabolic Pathways

PLoS Genet
PMCID: 4256263
PMID: 25474404
DOI: 10.1371/journal.pgen.1004816

[…] phylogeny reconciliation was performed in notung using its duplication, transfer, loss and ILS aware parsimony-based algorithm –, . Ambiguity in the fungal species phylogeny and low branch support in ECgene trees were handled through a multi-step approach. First, ECgene tree branches with less than 0.90 SH-like local support were collapsed using treecollapsercl v4 ( […]


Integrating Genomic, Transcriptomic, and Interactome Data to Improve Peptide and Protein Identification in Shotgun Proteomics

J Proteome Res
PMCID: 4059263
PMID: 24792918
DOI: 10.1021/pr500194t

[…] mples against the database, they confirmed the translation of 224 hypothetical human proteins and over 40 alternative splicing events. Other studies use three-frame translation of mRNA sequences from ECgene, a comprehensive alternative splicing sequence database with splice variants predicted by EST clustering, to generate databases for integrating with the ENSEMBL database., Since alternative spl […]


Alternative Splicing for Diseases, Cancers, Drugs, and Databases

Sci World J
PMCID: 3674688
PMID: 23766705
DOI: 10.1155/2013/703568

[…] G-rich sequences which modulate the 3′ end processing of pre-mRNAs.Additionally, several comprehensive databases for alternative splicing have been developed such as HOLLYWOOD [], ASD [], BIPASS [], ECgene [], ASPicDB [], AspAlt [], H-DBAS [], SPLOOCE [], and APPRIS []. For example, the ECgene provides EST and serial analysis of gene expression (SAGE) data-based annotation and visualization for a […]


Review: Alternative Splicing (AS) of Genes As An Approach for Generating Protein Complexity

Curr Genomics
PMCID: 3664468
PMID: 24179441
DOI: 10.2174/1389202911314030004

[…] reference sequence and then aligning it with a linked sequence in UniGene and dbEST []. Human-transcriptome DataBase for Alternative Splicing (H-DBAS) is a unique database of AS human transcripts [].ECgene provides functional annotation for alternatively spliced genes. It includes the genome-based transcript modeling for alternative splicing (AS), domain analysis with Gene Ontology (GO) annotatio […]


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ECgene institution(s)
Division of Molecular Life Sciences, Ewha Womans University, Seoul, Korea; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Korea; Bioinformatics Team, Electronics and Telecommunications Research Institute (ETRI), Gajeong-Dong, Daejeon, Korea; Department of Chemistry and Biochemistry, Center for Computational Biology, Institute for Genomics and Proteomics, Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, USA; Korean Bioinformation Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon, Korea
ECgene funding source(s)
Supported by the Korean Ministry of Science and Technology through the bioinformatics research program (Grant No. 2006-01305) and by the Korean Institute for Information Technology Advancement (IITA) under the Korean Ministry of Information and Communication.

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