edira statistics

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Citations per year

Number of citations per year for the bioinformatics software tool edira

Tool usage distribution map

This map represents all the scientific publications referring to edira per scientific context
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edira specifications


Unique identifier OMICS_09009
Name edira
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
Computer skills Advanced
Stability Stable
Maintained Yes


No version available


  • person_outline Martin Schäfer

Publication for edira

edira citations


Integrative analysis of genome wide gene copy number changes and gene expression in non small cell lung cancer

PLoS One
PMCID: 5675410
PMID: 29112949
DOI: 10.1371/journal.pone.0187246

[…] umber estimates. To assess the correlation between GE and CN, the externally centered correlation coefficient (ECCC) was calculated, essentially as described by Schäfer et al. [] using the R package ‘edira’ []. For each probe set, ECCC considers the equally directed deviations of CN and GE intensities from the median of an external reference group. The HapMap data set [] was used as external refer […]


An Integrative Analysis to Identify Driver Genes in Esophageal Squamous Cell Carcinoma

PLoS One
PMCID: 4605796
PMID: 26465158
DOI: 10.1371/journal.pone.0139808
call_split See protocol

[…] Our analysis flow in this study is summarized in . To identify differentially expressed genes associated with CNAs in ESCC, we applied gene expression and aCGH data to the edira algorithm []. This algorithm is characterized as the bivariate approach with the assessment of the equally directed abnormality of copy number and gene expression. Instead of a two-step approach […]

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edira institution(s)
Collaborative Research Center 475; Department of Statistics, TU Dortmund University, Dortmund, Germany; Department of Biostatistics, Johns Hopkins University, Baltimore, USA; Galenus-G.H. AG, Basel, Switzerland; MLL Munich Leukemia Laboratory, Munich; Department of Medical Informatics and Biomathematics, University of Münster, Münster, Germany
edira funding source(s)
Deutsche Forschungsgemeinschaft (SFB 475, ‘Reduction of Complexity in Multivariate Data Structures’); the European Leukemia Network of Excellence (LSHC-CT-2004); COST action BM0801 Translating genomic and epigenetic studies of MDS and AML (EuGESMA)

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