|Application:||Gene expression microarray analysis|
|Number of samples:||18|
|Release date:||Jan 13 2010|
|Taxon:||Homo sapiens, Rattus norvegicus|
|Dataset link||Liver of rat offsprings exposed perinatally to low doses of 2,2',4,4'-tetrabromodiphenyl ether|
Dams were randomly distributed among two groups (3 dams per group) and exposed by caudal injection (0.3 ml/kg body weight) from GD 15 to PND 20 every 5 days (a total of 6 injections/dam). Dams of the control group received vehicle: ethanol 95%, Cremophor EL, and sterile water (1:1:8, v/v); dams of exposed group 1 received 0.002 mg/kg body weight (BW) of BDE-47 in vehicle, and dams of exposed group 2 received 0.2 mg/kg body weight (BW) of BDE-47 in vehicle. Dams and pups were kept together until weaning on PND 21. After weaning, dams, male and female pups were separated. One male and one female pup per litter were selected randomly and sacrificed by decapitation on PND 27. Total RNA was extracted from liver samples of these pups and used for microarray analysis.
Citations per year
Environ Health Perspect