EigenTHREADER specifications


Unique identifier OMICS_17092
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Python
License Apache License version 2.0
Computer skills Advanced
Stability Stable
Source code URL http://bioinfadmin.cs.ucl.ac.uk/downloads/eigenTHREADER/?C=D;O=A
Maintained Yes




No version available



  • person_outline Pr. David T. Jones

Publication for EigenTHREADER

EigenTHREADER citations


Improved protein contact predictions with the MetaPSICOV2 server in CASP12

PMCID: 5836854
PMID: 28901583
DOI: 10.1002/prot.25379

[…] s a maximum for the FM targets when N eff approaches 1,500. In these cases, MetaPSICOV2 was able to achieve a precision of 100% for two targets, T0886‐D1 and T0886‐D2. Further to our previous work on EigenTHREADER (Buchan and Jones ), we note that with such high precision over the top L/5 contacts, it should be possible to uniquely specify the fold of the domain. For the FM/TBM targets precision a […]


An overview of comparative modelling and resources dedicated to large scale modelling of genome sequences

Acta Crystallogr D Struct Biol
PMCID: 5571743
PMID: 28777078
DOI: 10.1107/S2059798317008920

[…] econdary-structural fragments and uses a simulated-annealing algorithm to assemble the most probable three-dimensional protein structure (Kleywegt & Jones, 1997). Recently, the Jones group introduced EigenTHREADER, a novel fold-recognition method which combines standard threading methods with their in-house MetaPSICOV contact-prediction constraints method (Buchan & Jones, 2017). Phyre2 (Kelley et […]

EigenTHREADER institution(s)
Department of Computer Science, University College London, London, UK
EigenTHREADER funding source(s)
Supported by the Biotechnology & Biological Sciences Research Council (BBSRC) UK, Grant BB/M011712/1.

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