ELASPIC specifications

Information


Unique identifier OMICS_11218
Name ELASPIC
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Philip Kim

Information


Unique identifier OMICS_11218
Name ELASPIC
Software type Pipeline/Workflow
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Source code URL https://gitlab.com/kimlab/elaspic
Maintained Yes

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Versioning


No version available

Maintainer


  • person_outline Philip Kim

Publications for ELASPIC

ELASPIC citation

library_books

Structure Based Thermostability Prediction Models for Protein Single Point Mutations with Machine Learning Tools

2015
PLoS One
PMCID: 4567301
PMID: 26361227
DOI: 10.1371/journal.pone.0138022

[…] lue in MUpro, I-Mutant 2.0 LSE, PROTS, and PROTS_RF model were obtained from a 5-fold cross validation, while we ran a 10-fold cross validation with our models. PoPMuSiC-2.0, Prethermut, ProMaya, and ELASPIC were evaluated with a 20-fold cross validation. The Potapov_09 (Core) data set [] which contains 2104 mutations in 79 proteins was used for training and testing with these 4 methods. We conver […]

ELASPIC institution(s)
Donnelly Center for Cellular and Biomolecular Research, University of Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, ON, Canada; Department of Computer Science, University of Toronto, Toronto, ON, Canada; Department of Electrical and Electronic Engineering, Universidad Nacional De Colombia, Manizales, Colombia
ELASPIC funding source(s)
A NSERC Discovery Grant (#386671)

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