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ELM specifications


Unique identifier OMICS_02432
Name ELM
Alternative name Eukaryotic Linear Motif resource
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Toby J. Gibson

Publications for Eukaryotic Linear Motif resource

ELM citations


Evolutionary analyses of myosin genes in trypanosomatids show a history of expansion, secondary losses and neofunctionalization

Sci Rep
PMCID: 5778035
PMID: 29358582
DOI: 10.1038/s41598-017-18865-y

[…] oteins (e-value cutoff E-5) searching for non-annotated ORFs or remnants of the genes.CD-search on NCBI Conserved Domain Database (CDD), SMART (Single Modular Architecture Research Tool) and ELM (The Eukaryotic Linear Motif resource) were used to find protein domains and motifs using default parameters.Amino acid alignments were obtained by PSI-Coffee. Alignments were visualized and edited using t […]


Coevolving MAPK and PID phosphosites indicate an ancient environmental control of PIN auxin transporters in land plants

PMCID: 5814726
PMID: 29197077
DOI: 10.1002/1873-3468.12929

[…] In silico analysis of Arabidopsis PIN protein sequences by using the Eukaryotic Linear Motif Resource (ELM) identified several putative MAPK phosphorylation sites. Phylogenetic analysis revealed a strikingly high degree of conservation of three sites, suggesting a pro […]


A loss of Pdxk model of Parkinson disease in Drosophila can be suppressed by Buffy

BMC Res Notes
PMCID: 5468966
PMID: 28606139
DOI: 10.1186/s13104-017-2526-8
call_split See protocol

[…] r for Biotechnology Information (NCBI; http://www.ncbi.nlm.nih.gov/protein/) and the domains were identified using the NCBI Conserved Domain Database (CDD; http://www.ncbi.nlm.nih.gov/cdd) [] and the Eukaryotic Linear Motif resource (ELM; http://elm.eu.org/) [] which focuses on annotation and detection of eukaryotic linear motifs (ELMs) or short linear motifs (SLiMs). The alignment of sequences wa […]


PD L1 Is Not Constitutively Expressed on Tasmanian Devil Facial Tumor Cells but Is Strongly Upregulated in Response to IFN ╬│ and Can Be Expressed in the Tumor Microenvironment

Front Immunol
PMCID: 5145852
PMID: 28018348
DOI: 10.3389/fimmu.2016.00581

[…] edict membrane topology and SignalP 4.1 server () and Phobius to predict signal peptides. The ExPASy server ProtParam tool () was used to predict molecular weight and extinction coefficients, and the Eukaryotic Linear Motif resource () was used to predict immunoreceptor tyrosine-based inhibitory motif (ITIM) and immunoreceptor tyrosine-based switch motif (ITSM) sites. Predicted protein structures […]


Genome wide identification, characterisation and expression profiles of calcium dependent protein kinase genes in barley (Hordeum vulgare L.)

J Appl Genet
PMCID: 5243917
PMID: 27447459
DOI: 10.1007/s13353-016-0357-2

[…] ermined using Scipio (http://www.webscipio.org/) based on the corresponding protein sequences (Keller et al. ). The presence of myristoylation motifs at the N-terminal domain were predicted using the Eukaryotic Linear Motif resource (http://elm.eu.org; Dinkel et al. ). The localisations of ancestral duplications shared between barley and rice was determined by mapping previously identified sequenc […]


Reconstruction of the High Osmolarity Glycerol (HOG) Signaling Pathway from the Halophilic Fungus Wallemia ichthyophaga in Saccharomyces cerevisiae

Front Microbiol
PMCID: 4904012
PMID: 27379041
DOI: 10.3389/fmicb.2016.00901

[…] onsortium, 2012; http://www.uniprot.org/; July 2015) and the SMART software (http://smart.embl-heidelberg.de/; June 2015). The proline-rich motifs of WiPbs2 and ScPbs2 were annotated according to the Eukaryotic Linear Motif Resource (http://elm.eu.org/; July 2015) and the literature. The physicochemical parameters of the protein sequences were obtained with the ProtParam ExPasy program (http://web […]

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ELM institution(s)
Structural and Computational Biology, European Molecular Biology Laboratory, Heidelberg, Germany; Health Services Research Unit, Operational Direction Public Health and Surveillance, Scientific Institute of Public Health (WIV-ISP), Brussels, Belgium; Ruprecht-Karls-Universit├Ąt, Heidelberg, Germany; Conway Institute of Biomolecular and Biomedical Sciences, University College Dublin, Dublin, Ireland

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