eMatchSite pipeline

eMatchSite specifications

Information


Unique identifier OMICS_10538
Name eMatchSite
Software type Package/Module
Interface Command line interface
Restrictions to use None
Input data two protein structures
Input format PDB
Output data A single file that containing: numerical scores for the constructed alignment of binding sites, aligned residue pairs with the corresponding Cα-Cα distances, transformation matrices to superpose the second protein onto the first protein, and the coordinates of the second protein upon the superposition of two binding sites.
Output format PDB
Operating system Unix/Linux
Programming languages C++
License GNU General Public License version 2.0
Computer skills Advanced
Stability Stable
Requirements zlib, gzstream, libsvm
Maintained Yes

Versioning


Add your version

Maintainer


  • person_outline Michal Brylinski <>

Additional information


http://brylinski.cct.lsu.edu/content/ematchsite-manual

Information


Unique identifier OMICS_10538
Name eMatchSite
Interface Web user interface
Restrictions to use None
Input data two protein structures
Input format PDB
Output data A single file that containing: numerical scores for the constructed alignment of binding sites, aligned residue pairs with the corresponding Cα-Cα distances, transformation matrices to superpose the second protein onto the first protein, and the coordinates of the second protein upon the superposition of two binding sites.
Output format PDB
Programming languages C++
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Michal Brylinski <>

Additional information


http://brylinski.cct.lsu.edu/content/ematchsite-manual

Publications for eMatchSite

eMatchSite citation

2018
PMCID: 5847522

[…] in npc2 have an effect on cholesterol binding.60–64 furthermore, mutations of m79, v81, and v83 block sterol transport making npc2 a promising drug target to treat npc diseases.65 interestingly, ematchsite detected a significant structure similarity between the cholesterol-binding pocket of npc2 and the steroid-binding pocket of cytochrome p450 aromatase (cyp19a1), an enzyme involved […]

eMatchSite institution(s)
Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, USA
eMatchSite funding source(s)
Supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number R35GM119524.

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