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DMDD / Deciphering the Mechanisms of Developmental Disorders
Contains image and phenotype data for embryonic lethal knockout mice. DMDD is database allowing to search by gene, phenotype or tissue type. The data sheds new light on genes that are critical for embryo development and survival. High-resolution 3D image analysis and tissue histology are used to identify abnormalities in both embryos and placentas from embryonic lethal lines. It provides Full-resolution images, phenotypes annotated on the relevant images and Phenotype penetrance data for each line. The database also includes gene expression profiles for embryos from knockout lines.
BRAINS Imagebank / Brain Images of Normal Subjects Imagebank
A collection of anonymised images and associated clinical data. BRAINS Imagebank includes ‘normal’ individuals at all ages (from prenatal to old age). The data were collected from individuals participating in healthy volunteer studies, or control groups. The imagebank is a searchable database of integrated data sets already collected as part of research studies which include healthy (or control) subjects. New data will be added as they become available. These studies include detailed MRI using a range of sequences, and associated data, e.g. pregnancy details (for neonatal data), demographic details, current and prior socioeconomic status, education, health, medication use and cognitive tests.
The Multi-Dimensional Human Embryo
Improves the distribution of human embryological image data. The Multi-Dimensional Human Embryo intends to collect 3D magnetic resonance data of normal human embryos from Carnegie stages 10–23. It produces a series of images of each embryo in three principal imaging planes (transverse, coronal, and sagittal), a series of volume-rendered images to represent surface features of each whole embryo, and a series of images to demonstrate time-lapse growth of the human embryo.
Provides a molecular atlas of the developing lung. LungMAP includes mouse and human data for cross correlation of developmental processes across species. This online resource is available through a web portal for presentation of results and public sharing of data sets. It establishes a repository of young human lung tissues obtained through organ donor organizations. It also develops a comprehensive lung ontology that incorporates the latest findings of LungMAP consortium. The database contains transcriptomic, proteomic, and lipidomic data sources.
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