Unlock your biological data
Enhancers are of short regulatory DNA elements. They can be bound with proteins (activators) to activate transcription of a gene, and hence play a critical role in promoting gene transcription in eukaryotes. With the avalanche of DNA sequences generated in the post genomic age, it is a challenging task to develop computational methods for timely identifying enhancers from extremely complicated DNA sequences.
(Liu et al., 2016) iEnhancer-2L: a two-layer predictor for identifying enhancers and their strength by pseudo k -tuple nucleotide composition. Bioinformatics.