EnigmaVis specifications


Unique identifier OMICS_19297
Name EnigmaVis
Interface Web user interface
Restrictions to use None
Input data A GWAS data.
Input format CSV
Programming languages Javascript
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Arthur Toga <>

Publication for EnigmaVis

EnigmaVis in publications

PMCID: 5826945
PMID: 29483533
DOI: 10.1038/s41467-018-03247-3

[…] was used to perform the meta-analysis. the associations between esnps of alms1, glt8d1, and csnk2b, and hippocampal structure were extracted from the enigma website (https://www.enigma-brain.org/enigmavis/visualizer/visualizer). more detailed information about the enigma (including sample description, mri collection, genotyping, quality control, and statistical analyses can be found […]

PMCID: 5152628
PMID: 27846195
DOI: 10.1097/FPC.0000000000000250

[…] genes and variants were queried in the gtex portal (http://www.gtexportal.org/), data source: gtex analysis release v6 (dbgap accession phs000424.v6.p1) , braineac (http://braineac.org/) , and enigmavis (http://enigma.ini.usc.edu/) . these resources include gwas results for a few imaging genetics studies for human hippocampal and intracranial volumes (icvs) , lentiform nucleus volume , […]

PMCID: 4192369
PMID: 25280473
DOI: 10.1186/1471-2164-15-850

[…] volume from healthy subjects and patients was generated for gwas meta-analyses by the enhancing neuro imaging genetics through meta-analysis (enigma) network [, , ] and can be visualised with enigmavis []. association analyses used multiple linear regression with hippocampus volume as a dependent variable and the additive dosage of each snp as an independent variable, controlling […]

PMCID: 4051592
PMID: 24514566
DOI: 10.1038/mp.2013.197

[…] with total brain volume, the brain phenotype most closely related to cortical thickness available in this data set. association of rs7171755 with brain volume was performed using the online tool enigmavis, generating an interactive association plot. only the healthy subsample (n=5775) of enigma, for which this brain volume was available, were included in the meta-analysis., to provide […]

PMCID: 3689744
PMID: 23805179
DOI: 10.1371/journal.pone.0064872

[…] for association signals with bilateral hippocampal volume for the aforementioned snps (if available) and all other available intragenic snps in a window of +/−100 kb of our top snps (i) using enigmavis, an online interactive visualization tool of genome-wide association signals of the enigma study , and (ii) estimating similar linear regression models as described above using the imagen […]

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EnigmaVis institution(s)
Laboratory of Neuro Imaging, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA; Quantitative Genetics, Queensland Institute of Medical Research, Brisbane, QLD, Australia
EnigmaVis funding source(s)
Supported by the National Institutes of Health (NIH) and the National Center for Research Resources (NCRR) grant P41 RR013642, the NSF GRFP grant DGE-0707424, an Australian Research Council Future Fellowship FT110100548, the NIH Postdoctoral Training Grant in Neurobehavioral Genetics, and NIH grants U01 AG024904, EB008432, P41 RR013642, HD050735, AG036535, EB008281.

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