Enrichr pipeline

Enrichr specifications

Information


Unique identifier OMICS_06341
Name Enrichr
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Avi Ma’ayan <>

Information


Unique identifier OMICS_06341
Name Enrichr
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Computer skills Medium
Stability Stable
Mobile operating system iOS
Maintained Yes

Versioning


Add your version

Maintainer


  • person_outline Avi Ma’ayan <>

Publication for Enrichr

Enrichr IN pipelines

 (10)
2018
PMCID: 5799454
PMID: 29402919
DOI: 10.1038/s41598-018-20679-5

[…] ontology (go) analysis for biological processes, cellular components and molecular function and a kegg pathway analysis (kyoto encyclopedia of genes and genomes http://www.genome.ad.jp/kegg) via enrichr web tool56,57., non-coding rnas pathway analysis was performed. lncpath r package was used to map differentially expressed lncrnas on a lncrna-mrna relationship network, to evaluate […]

2018
PMCID: 5840357
PMID: 29511172
DOI: 10.1038/s41419-018-0411-6

[…] and adjusted p < 0.05 were selected as the rbko-related degs. totally 677 degs were identified. the heatmap was generated using heatmapper55. the function enrichment of deg was performed using enrichr33,34, the pathways with adjusted p < 0.05 were chosen to report., total rna was isolated from dissected peripheral retina using the tripure isolation reagent (roche, usa) or rneasy mini […]

2018
PMCID: 5955139
PMID: 29774125
DOI: 10.18632/oncotarget.25188

[…] and used to define log fold-change and average expression values. transcripts with maximum global expression greater than 1 and log fold-change greater than 1.5 were selected for go analysis in enrichr [16]. heat maps were visualized with partek genomics suite 6.6 (st. louis, mo) and scatterplots were visualized with stata/mp 14.2 (college station, tx)., at least three independent […]

2017
PMCID: 5345195
PMID: 28283027
DOI: 10.1186/s40478-017-0421-0

[…] the exosomal content of each module with the funrich tool [81], exploiting the extracellular vesicles database [52]. next, we performed gene ontology and pathway analysis using a web based tool, enrichr [56], as well as cluego and cluepedia [14] implemented in cytoscape and supplemented with enrichment analysis in wgcna. complementary to these analyses, our functional interpretation of gene […]

2017
PMCID: 5482631
PMID: 28415592
DOI: 10.18632/oncotarget.16415

[…] the tumor and matched non-tumorous tissues were identified with pair-wise t test and the significant threshold was set as adjusted p-value of less than 0.05 and |log2(fold change, fc)| > = 1. enrichr was used to do functional enrichment analysis like gene ontology (go) and kegg pathway [7]. the significant threshold for enrichment was set as p < 0.1. in addition, the list […]

Enrichr institution(s)
Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, One Gustave, New York, NY, USA

Enrichr reviews

 (2)
star_border star_border star_border star_border star_border
star star star star star

Satarupa Banerjee

star_border star_border star_border star_border star_border
star star star star star
Web
Best GSEA tool I have used

Dr Nick

star_border star_border star_border star_border star_border
star star star star star
Web
Useful if you want an ultra-fast glimpse at the characteristics of a gene/protein list. However, it does not take regulatory direction, nor expression values into account. Some of the databases against which it compares are in need of updating. Also, I question the statistical validity of their scoring system. Nevertheless, while it should never be used as an endpoint for analyses, it is quite helpful in pointing you in directions for further inquiry and provides quick graphic summaries for easy presentation.