Offers personalized recommendations based on pharmacogenomics evidence. ePGA is a web-based application that combines: (i) information retrieval on state of the art PGx variants, genes, drugs, and their associations, (ii) matching of individual genotype-profiles with PGx gene haplotypes and inference of corresponding diplotype profiles, accompanied by respective summary statistics, (iii) automated linkage of the inferred diplotypes with respective clinical annotations, recommendations and dosing guidelines and (iv) update services on newly discovered PGx variants and haplotypes.
Institute of Computer Science, Foundation for Research and Technology, Heraklion, Crete, Greece; Department of Pharmacy, School of Health Sciences, University of Patras, Rio, Patras, Greece
ePGA funding source(s)
The reported work was funded by the eMoDiA (electronicMolecular Diagnostics Assistant) project (11_ΣYN10145) under the ' Competitiveness and Entrepreneurship ' (OPCE II Greek-EU) operational programand the RD-Connect project (FP7-305444; European Commission).