Bioinformatics tools for epigenomics

For didactic purposes, epigenetic modifications can be grouped into three main categories: DNA methylation, histone modifications and nucleosome positioning (Portela and Esteller, 2010). An altered pattern of epigenetic modifications is central to many common human diseases, including cancer (Esteller, 2007; Esteller, 2008).

DNA modifications
Nucleosome positioning
DNA-Protein interactions