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EpiJen specifications

Information


Unique identifier OMICS_06755
Name EpiJen
Interface Web user interface
Restrictions to use None
Programming languages Perl
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline EpiJen Team <>

Publication for EpiJen

EpiJen in pipeline

2008
PMCID: 2569417
PMID: 18949050
DOI: 10.1371/journal.pone.0003525

[…] of the independent steps of the antigen processing pathway, and use a threshold on the summed score (e.g. mhc-pathway and netctl ), and those that eliminate epitope candidates at each step (e.g. epijen , mappp and the alternative implementation of mhc-pathway )., in this study we use the alternative implementation of the mhc-pathway model . we screen all possible peptide fragments of 14 […]


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EpiJen in publications

 (15)
PMCID: 5773588
PMID: 29348555
DOI: 10.1038/s41598-018-19456-1

[…] netctl was selected to predict the ctl epitopes because of its higher prescient execution on all execution parameters as compared to the recently developed servers namely mhc-pathway, mappp, and epijen. all the salivary protein sequences were submitted in the fasta format to predict the ctl epitope at the threshold score of 0.75 (default). those epitopes having a combined score of greater […]

PMCID: 5712781
PMID: 29225429
DOI: 10.6026/97320630013366

[…] [] reported a systematic platform for prediction of immunogenicity and mhc class i binding affinity. the platform integrates three quasi-independent modular servers: vaxijen for immunogenicity and epijen to predict peptide binding to mhc class i proteins. we however used mhc prediction first to identify as many epitopes as possible followed by screening and selection of epitopes that survive […]

PMCID: 5468442
PMID: 28659922
DOI: 10.3389/fimmu.2017.00684

[…] of proper linkers. hla a*0201-restricted epitopes derived from the l. infantum proteins and included in the chimeric peptides were predicted using the online available algorithms syfpeithi () and epijen () with a cutoff score adjusted to ≥18 and <50 nm, respectively (table ). syfpeithi was also used for the in silico prediction of potent h2-kb- or h2-db-restricted epitopes (table ). […]

PMCID: 4792444
PMID: 26977703
DOI: 10.1371/journal.pntd.0004511

[…] significance (p < 0.1 or bayes factor >50), were considered to be under positive selection., t-cell epitopes of the envelope gene of prototype dengue 2 virus were predicted using the epijen online server []. envelope protein sequence of denv-2 prototype strain (ngc 44 strain; genbank accession number: af038403) was submitted for epitope prediction. appropriate proteasomal and tap […]

PMCID: 4654883
PMID: 26589500
DOI: 10.1186/s13073-015-0245-0

[…] filtering scheme: only peptides possessing correctly cleaved c-termini and with sufficient affinity to tap are then subjected to the hla prediction. examples of tools implementing this approach are epijen [] and wapp [], both based around already existing prediction methods. netctl [] and netctlpan [] chose a different approach. here, instead of a step-wise filtering, the scores […]


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EpiJen institution(s)
Edward Jenner Institute for Vaccine Research, Compton, UK

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