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EpiJen specifications


Unique identifier OMICS_06755
Name EpiJen
Interface Web user interface
Restrictions to use None
Programming languages Perl
Computer skills Basic
Stability Stable
Maintained Yes


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Publication for EpiJen

EpiJen citations


Novel Immunoinformatics Approaches to Design Multi epitope Subunit Vaccine for Malaria by Investigating Anopheles Salivary Protein

Sci Rep
PMCID: 5773588
PMID: 29348555
DOI: 10.1038/s41598-018-19456-1
call_split See protocol

[…] set. NetCTL was selected to predict the CTL epitopes because of its higher prescient execution on all execution parameters as compared to the recently developed servers namely MHC-pathway, MAPPP, and EpiJen. All the salivary protein sequences were submitted in the FASTA format to predict the CTL epitope at the threshold score of 0.75 (default). Those epitopes having a combined score of greater tha […]


In Silico Validation of D7 Salivary Protein derived B and T cell Epitopes of Aedes aegypti as Potential Vaccine to Prevent Transmission of Flaviviruses and Togaviruses to Humans

PMCID: 5712781
PMID: 29225429
DOI: 10.6026/97320630013366

[…] l. [] reported a systematic platform for prediction of immunogenicity and MHC class I binding affinity. The platform integrates three quasi-independent modular servers: VaxiJen for immunogenicity and EpiJen to predict peptide binding to MHC class I proteins. We however used MHC prediction first to identify as many epitopes as possible followed by screening and selection of epitopes that survive pr […]


A Poly(Lactic co Glycolic) Acid Nanovaccine Based on Chimeric Peptides from Different Leishmania infantum Proteins Induces Dendritic Cells Maturation and Promotes Peptide Specific IFNγ Producing CD8+ T Cells Essential for the Protection against Experimental Visceral Leishmaniasis

Front Immunol
PMCID: 5468442
PMID: 28659922
DOI: 10.3389/fimmu.2017.00684

[…] use of proper linkers. HLA A*0201-restricted epitopes derived from the L. infantum proteins and included in the chimeric peptides were predicted using the online available algorithms SYFPEITHI () and EpiJen () with a cutoff score adjusted to ≥18 and <50 nM, respectively (Table ). SYFPEITHI was also used for the in silico prediction of potent H2-Kb- or H2-Db-restricted epitopes (Table ). The chimer […]


Expression and purification of truncated diphtheria toxin, DT386, in Escherichia coli: An attempt for production of a new vaccine against diphtheria

PMCID: 5122833
PMID: 27920826
DOI: 10.4103/1735-5362.192496
call_split See protocol

[…] B-cell epitope prediction (BCPred) (10) and EpiJen (11) web-based servers have been used to predict the linear B-cell and T-cell epitopes of DT386 protein (GenBank: BAL14546.1). In order to predict the B-cell epitopes, BCpreds: B-cell epitope p […]


Evolutionary Analysis of Dengue Serotype 2 Viruses Using Phylogenetic and Bayesian Methods from New Delhi, India

PLoS Negl Trop Dis
PMCID: 4792444
PMID: 26977703
DOI: 10.1371/journal.pntd.0004511
call_split See protocol

[…] T-cell epitopes of the envelope gene of prototype dengue 2 virus were predicted using the EpiJen online server []. Envelope protein sequence of DENV-2 prototype strain (NGC 44 strain; GenBank Accession Number: AF038403) was submitted for epitope prediction. Appropriate proteasomal and Tap […]


Immunoinformatics and epitope prediction in the age of genomic medicine

Genome Med
PMCID: 4654883
PMID: 26589500
DOI: 10.1186/s13073-015-0245-0

[…] a filtering scheme: only peptides possessing correctly cleaved C-termini and with sufficient affinity to TAP are then subjected to the HLA prediction. Examples of tools implementing this approach are EpiJen [] and WAPP [], both based around already existing prediction methods. NetCTL [] and NetCTLpan [] chose a different approach. Here, instead of a step-wise filtering, the scores of the different […]

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EpiJen institution(s)
Edward Jenner Institute for Vaccine Research, Compton, UK

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