EpiJen statistics

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Citations per year

Number of citations per year for the bioinformatics software tool EpiJen

Tool usage distribution map

This map represents all the scientific publications referring to EpiJen per scientific context
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Associated diseases

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EpiJen specifications


Unique identifier OMICS_06755
Name EpiJen
Interface Web user interface
Restrictions to use None
Programming languages Perl
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline EpiJen Team

Publication for EpiJen

EpiJen citations


Novel Immunoinformatics Approaches to Design Multi epitope Subunit Vaccine for Malaria by Investigating Anopheles Salivary Protein

Sci Rep
PMCID: 5773588
PMID: 29348555
DOI: 10.1038/s41598-018-19456-1
call_split See protocol

[…] set. NetCTL was selected to predict the CTL epitopes because of its higher prescient execution on all execution parameters as compared to the recently developed servers namely MHC-pathway, MAPPP, and EpiJen. All the salivary protein sequences were submitted in the FASTA format to predict the CTL epitope at the threshold score of 0.75 (default). Those epitopes having a combined score of greater tha […]


In Silico Validation of D7 Salivary Protein derived B and T cell Epitopes of Aedes aegypti as Potential Vaccine to Prevent Transmission of Flaviviruses and Togaviruses to Humans

PMCID: 5712781
PMID: 29225429
DOI: 10.6026/97320630013366

[…] l. [] reported a systematic platform for prediction of immunogenicity and MHC class I binding affinity. The platform integrates three quasi-independent modular servers: VaxiJen for immunogenicity and EpiJen to predict peptide binding to MHC class I proteins. We however used MHC prediction first to identify as many epitopes as possible followed by screening and selection of epitopes that survive pr […]


A Poly(Lactic co Glycolic) Acid Nanovaccine Based on Chimeric Peptides from Different Leishmania infantum Proteins Induces Dendritic Cells Maturation and Promotes Peptide Specific IFNγ Producing CD8+ T Cells Essential for the Protection against Experimental Visceral Leishmaniasis

Front Immunol
PMCID: 5468442
PMID: 28659922
DOI: 10.3389/fimmu.2017.00684

[…] use of proper linkers. HLA A*0201-restricted epitopes derived from the L. infantum proteins and included in the chimeric peptides were predicted using the online available algorithms SYFPEITHI () and EpiJen () with a cutoff score adjusted to ≥18 and <50 nM, respectively (Table ). SYFPEITHI was also used for the in silico prediction of potent H2-Kb- or H2-Db-restricted epitopes (Table ). The chimer […]


Expression and purification of truncated diphtheria toxin, DT386, in Escherichia coli: An attempt for production of a new vaccine against diphtheria

PMCID: 5122833
PMID: 27920826
DOI: 10.4103/1735-5362.192496
call_split See protocol

[…] B-cell epitope prediction (BCPred) (10) and EpiJen (11) web-based servers have been used to predict the linear B-cell and T-cell epitopes of DT386 protein (GenBank: BAL14546.1). In order to predict the B-cell epitopes, BCpreds: B-cell epitope p […]


Evolutionary Analysis of Dengue Serotype 2 Viruses Using Phylogenetic and Bayesian Methods from New Delhi, India

PLoS Negl Trop Dis
PMCID: 4792444
PMID: 26977703
DOI: 10.1371/journal.pntd.0004511
call_split See protocol

[…] T-cell epitopes of the envelope gene of prototype dengue 2 virus were predicted using the EpiJen online server []. Envelope protein sequence of DENV-2 prototype strain (NGC 44 strain; GenBank Accession Number: AF038403) was submitted for epitope prediction. Appropriate proteasomal and Tap […]


Immunoinformatics and epitope prediction in the age of genomic medicine

Genome Med
PMCID: 4654883
PMID: 26589500
DOI: 10.1186/s13073-015-0245-0

[…] a filtering scheme: only peptides possessing correctly cleaved C-termini and with sufficient affinity to TAP are then subjected to the HLA prediction. Examples of tools implementing this approach are EpiJen [] and WAPP [], both based around already existing prediction methods. NetCTL [] and NetCTLpan [] chose a different approach. Here, instead of a step-wise filtering, the scores of the different […]

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EpiJen institution(s)
Edward Jenner Institute for Vaccine Research, Compton, UK

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