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EpiToolKit specifications


Unique identifier OMICS_07594
Name EpiToolKit
Interface Web user interface
Restrictions to use None
Computer skills Basic
Version 2.0
Stability Stable
Maintained No


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Publications for EpiToolKit

EpiToolKit citations


Population level distribution and putative immunogenicity of cancer neoepitopes

BMC Cancer
PMCID: 5899330
PMID: 29653567
DOI: 10.1186/s12885-018-4325-6

[…] in a patient-specific manner [–]. With little variation, these are the criteria applied by all computational tools for neoepitope prediction from tumor genomic sequencing data, including Epi-Seq [], EpiToolKit [], pVAC-Seq [], INTEGRATE-neo [], TSNAD [], MuPeXI [], and CloudNeo [].Our central assertion is that the immunogenicity of a neoepitope is directly related to its novelty: that is, the ext […]


Vaccines Meet Big Data: State of the Art and Future Prospects. From the Classical 3Is (“Isolate–Inactivate–Inject”) Vaccinology 1.0 to Vaccinology 3.0, Vaccinomics, and Beyond: A Historical Overview

PMCID: 5845111
PMID: 29556492
DOI: 10.3389/fpubh.2018.00062

[…] ine discovery and design (, ). Databases of vaccine candidates, such as MalVac (), or Vaxar (), software tools such as Vaxjo (), VIOLIN (–), NERVE (), Vaxign (), Vacceed (), Jenner-predict server (), EpiToolKit (), iVax (), or VaxiJen (), have been specifically implemented for vaccinology to enable prediction of vaccine antigens or adjuvants.A successful example of rationally designed web-based va […]


Designing string of beads vaccines with optimal spacers

Genome Med
PMCID: 4728757
PMID: 26813686
DOI: 10.1186/s13073-016-0263-6

[…] c []. The model was implemented in Python 2.7 using Pyomo 4.0 [] and solved with ILOG CPLEX 12.5 (www.ilog.com) and the Lin–Kernighan–Helsgaun heuristic []. The complete framework was integrated into EpiToolKit, a web-based platform for rational vaccine design. It can be accessed at www.epitoolkit.de under Spacer Design []. The source code and example files can be found at https://github.com/FRED- […]


Immunoinformatics and epitope prediction in the age of genomic medicine

Genome Med
PMCID: 4654883
PMID: 26589500
DOI: 10.1186/s13073-015-0245-0

[…] ototyping integrating a larger number of algorithms into convenient scripting languages such as Python []. Furthermore, graphical workflow engines such as Galaxy [] do not require programming skills. EpiToolKit 2.0, for example, offers an immunoinformatics workbench with a wide range of functionalities in a single coherent graphical user interface []. […]


SITC/iSBTc Cancer Immunotherapy Biomarkers Resource Document: Online resources and useful tools a compass in the land of biomarker discovery

J Transl Med
PMCID: 3189883
PMID: 21929757
DOI: 10.1186/1479-5876-9-155

[…] It is an easy-to-use tool to determine a provably optimal set of epitopes with respect to overall immunogenicity in a specific individual or a target population, free of charge Website: http://www.epitoolkit.org/optitope Name: Cancer Central Clinical Database (C3D)Comment:Cancer Central Clinical Database (C3D) is a clinical trials data management system. C3D collects clinical trial data using s […]


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EpiToolKit institution(s)
Center for Bioinformatics, University of Tübingen, Tübingen, Germany

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