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Epitope selection

Epitope-based vaccines (EVs) have recently been attracting significant interest. They trigger an immune response by confronting the immune system with immunogenic peptides derived from, e.g. viral- or cancer-related proteins. Binding of these…
NetMHCpan
Web

NetMHCpan

Allows prediction of peptide binding affinity. NetMHCpan is a simple…

Allows prediction of peptide binding affinity. NetMHCpan is a simple pan-specific machine learning method. It improves predictive performance by characterizing the binding specificity of a given…

PEPVAC
Web

PEPVAC Promiscuous EPitope-based VACcine

Allows prediction of promiscuous epitopes to five human leukocyte antigen (HLA)…

Allows prediction of promiscuous epitopes to five human leukocyte antigen (HLA) I. PEPVAC combines predictions of supertypic peptide binders with the prediction of proteasomal cleavage using…

OptiTope
Web

OptiTope

Aims at assisting immunologists in designing epitope-based vaccines. OptiTope…

Aims at assisting immunologists in designing epitope-based vaccines. OptiTope maximizes overall immunogenicity with respect to the user's requirements. The overall immunogenicity of an epitope…

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EbolaVCR
Dataset

EbolaVCR Ebola Virus Computational Resources

In silico resources developed to facilitate scientific community fighting…

In silico resources developed to facilitate scientific community fighting against deadly virus EBOLA. EbolaVCR enlists possible vaccine candidates, therapeutic siRNAs and other related resources.…

Mosaic Vaccine…
Web

Mosaic Vaccine Tool Suite

A suite of on-line tools to design candidate vaccine proteins, and to assess…

A suite of on-line tools to design candidate vaccine proteins, and to assess antigen potential, using coverage of k-mers (as proxies for potential T-cell epitopes) as a metric. The vaccine design…

Hotspot Hunter
Web

Hotspot Hunter

A web-based computational system for large-scale screening and selection of…

A web-based computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes through analysis of antigenic diversity. Hotspot Hunter allows…

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