Unlock your biological data
Expression quantitative trait loci (eQTLs) are genetic variants that affect gene expression. In eQTL studies, one important task is to find eGenes or genes whose expressions are associated with at least one eQTL. The standard statistical method to determine whether a gene is an eGene requires association testing at all nearby variants and the permutation test to correct for multiple testing.
(Duong et al., 2016) Using genomic annotations increases statistical power to detect eGenes. Bioinformatics.