Consists of a drug repositioning data set. eRepo-ORP facilitates the orphan drug research. It was built on the results of a large-scale pocket matching between target sites for known drugs and those binding pockets identified in proteins linked to rare diseases. This database can serve to identify potential therapeutics for orphan diseases. It is searchable by the disorder name and identification according to Orphanet, as well as the DrugBank identifier.
Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, USA; Center for Computation & Technology, Louisiana State University, Baton Rouge, LA, USA; Division of Computer Science and Engineering, Louisiana State University, Baton Rouge, LA, USA
eRepo-ORP funding source(s)
Supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number R35GM119524.