EricScript specifications


Unique identifier OMICS_07348
Name EricScript
Alternative name chimEric tranScript detection algorithm
Software type Framework/Library
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Perl, R, Shell (Bash)
License GNU General Public License version 2.0
Computer skills Advanced
Version 0.5.1
Stability Stable
ada, BWA, SAMtools, Bedtools, seqtk, BLAT
Maintained Yes



Add your version


  • person_outline Matteo Benelli <>

Publication for chimEric tranScript detection algorithm

EricScript in publications

PMCID: 5916809
PMID: 29617662
DOI: 10.1016/j.celrep.2018.03.050

[…] to methodically identify fusion transcripts across the tcga rna-seq data corpus using the institute for systems biology (isb) cancer genomics cloud. these tools include star-fusion, breakfast, and ericscript (star methods). fusion calling across 9,624 tcga tumor samples from 33 cancer types identified a total of 25,664 fusion transcripts, with a 63.3% validation rate for the samples […]

PMCID: 5748704
PMID: 29240691
DOI: 10.3390/genes8120386

[…] ( was used for filtering off low-quality reads. paired end sequencing reads were mapped to human genome version hg19 and analyzed using software tool, ericscript to identify candidate fusion rnas []. fusions with ericscore less than 0.5 were filtered off. the occurrence and frequencies of candidate fusion rnas were then correlated to gender, age, […]

PMCID: 5704251
PMID: 29165374
DOI: 10.3390/genes8110338

[…] pearson correlation function., we downloaded raw rna-seq data from study srp058633, which contains three biological replicates of untreated cells or cells treated with 80 mm kcl for 1 h. software ericscript was used to identify candidate chimeric rnas. a cut off of ericscore at 0.5 was used. we then selected chimeric rnas that were at least duplicated in each group., we used the same osmotic […]

PMCID: 5737606
PMID: 28541529
DOI: 10.1093/nar/gkx453

[…] which prioritize potentially oncogenic events by read count, or by scores that lack an underlying null statistical model. we have tested machete against star-fusion, soapfuse (), as well as ericscript, the best performing algorithms as defined by a recent evaluation (). we have evaluated machete on a simulated negative control dataset () and a ‘mixed’ dataset which combines the negative […]

PMCID: 5090896
PMID: 27822312
DOI: 10.1186/s13040-016-0112-6

[…] the available gene fusion-finders methods [, ] do not explore the potentials of applying ml techniques to this classification problem. as far as we are aware of, only two gene fusion-finders, namely ericscript [] and defuse [], have explored adaboost. adaboost generates a set of hypotheses and combines them through weighted majority voting of the classes predicted by the individual hypotheses. […]

To access a full list of publications, you will need to upgrade to our premium service.

EricScript institution(s)
Diagnostic Genetic Unit, Laboratory Department, Careggi University Hospital, Florence, Italy

EricScript review

star_border star_border star_border star_border star_border
star star star star star

Shailesh Kumar

star_border star_border star_border star_border star_border
star star star star star
This is a very good tool to find the fusion transcripts in RNA-Seq datasets. I have cited this tool in my publications. We have analysed 10,000 paired-end RNA-Seq datasets with this tool. Very useful.