bookmark Pheg / Predictor of human essential genes Predicts human gene essentiality. Pheg is based on the λ-interval Z-curve. It can predict whether a query gene is essential using only the CDS region of a gene as input. The tool has the potential for applications in mining characteristics from other character sequences and can be used as a universal feature extraction method for DNA sequences. Considering the Pheg’s result is better than the results obtained in previous studies using integrated features, the gene essentiality of the human genome can be accurately reflected based on only the sequence information.