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Essential gene databases | Synthetic biology

Essential genes are genes that are considered to be ‘essential’ for the survival of an organism (Juhas et al., 2012; Acevedo-Rocha et al., 2013). The genome-wide identification of essential genes has been performed by single-gene knockout (Baba et al., 2006; de Berardinis et al., 2008), transposon mutagenesis (Liberati et al., 2006; Gallagher et al., 2007) and RNA interference (Ji et al., 2001). Source text: Wei et al., 2014.

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