An application ontology driven by the annotation and query needs of samples in omics datasets. EFO provides an integration framework for ontologies and combines parts of several biological ontologies such as UBERON anatomy, ChEBI chemical compounds, and Cell Ontology. The relationship between ontology descriptions of rare and common diseases and their phenotypes can offer insights into shared biological mechanisms and potential drug targets. The scope of EFO is to support the annotation, analysis and visualization of several domain specific ontologies.
European Bioinformatics Institute (EMBL-EBI), European Molecular Biology, Laboratory, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK; Centre for Therapeutic Target Validation, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
EFO funding source(s)
This work was supported by the CTTV, EMBL Core Funds and the BioMedBridges project funded by the European Commission FP7 Capacities Specific Programme, grant No. 284209.