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Expitope specifications

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Unique identifier OMICS_07440
Name Expitope
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Kerstin Haase

Publication for Expitope

Expitope citations

 (2)
library_books

Unbiased Identification of T Cell Receptors Targeting Immunodominant Peptide–MHC Complexes for T Cell Receptor Immunotherapy

2017
PMCID: 5737719
PMID: 28950731
DOI: 10.1089/hum.2017.122

[…] data. strong binding of an epitope to the hla is indicated by a percentage rank of <0.5 among all epitopes from the database. weak binders are indicated by a percentage rank of <2.0. the expitope server (http://webclu.bio.wzw.tum.de/expitope/) enables the search for epitopes from the human proteome, which may be targets of cross-reactivity for tcrs. according to results […]

library_books

In silico discovery of cancer specific peptide HLA complexes for targeted therapy

2016
BMC Bioinformatics
PMCID: 4955262
PMID: 27439771
DOI: 10.1186/s12859-016-1150-2

[…] sequences similar to the target peptide, followed by selection of the most similar peptides predicted to bind the hla allele of interest that are ubiquitously expressed [, ]. the recently published expitope webserver is designed to perform these steps in a systematic fashion []. the webserver combines blast searches (to identify similar peptides), and various prediction tools that predict […]


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Expitope institution(s)
Department of Genome Oriented Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universität München, Freising, Germany; Immune Monitoring Group, Helmholtz Zentrum Munich, Institute of Molecular Immunology, München, Germany; Medigene Immunotherapies GmbH a Subsidiary of Medigene AG, Planegg, Germany; Helmholtz Zentrum Munich, Institute of Bioinformatics and Systems Biology, Neuherberg, Germany; St Petersburg State Polytechnical University, St Petersburg Russia

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