Tests for differences in minor allele frequency between groups and is based on an extra-binomial variation model for pooled sequencing data. extraBinomial can analyse both rare and common variants with lower or more variable pool depths compared to the other methods.
No review has been posted.
No open issue.
Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Addenbrooke’s Hospital, Cambridge CB2 0XY, UK