|Application:||Gene expression microarray analysis|
|Number of samples:||55|
|Release date:||Oct 31 2017|
|Last update date:||Jan 24 2018|
|Dataset link||Submandibular lymph node, a key battleground for host-Yersinia pestis interaction: A transcriptomic study using non-human primate model|
Our study used African Green Monkeys that didn’t exhibited clear clinical symptoms for nearly two days after intranasal challenge with Y. pestis and succumbed within a day after showing the first signs of clinical discomfort. Colonization of Y. pestis was detected in blood one day post-infection although blood transcripts were found to be altered immediately after the pathogenic assault. The organs of the respiratory tract and those adjacent, such as lungs and submandibular lymph nodes, accumulated significant Y. pestis colonization immediately after pathogenic challenge.