Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 55
Release date: Oct 31 2017
Last update date: Jan 24 2018
Access: Public
Diseases: Yersinia Infections
Dataset link Submandibular lymph node, a key battleground for host-Yersinia pestis interaction: A transcriptomic study using non-human primate model

Experimental Protocol


Our study used African Green Monkeys that didn’t exhibited clear clinical symptoms for nearly two days after intranasal challenge with Y. pestis and succumbed within a day after showing the first signs of clinical discomfort. Colonization of Y. pestis was detected in blood one day post-infection although blood transcripts were found to be altered immediately after the pathogenic assault. The organs of the respiratory tract and those adjacent, such as lungs and submandibular lymph nodes, accumulated significant Y. pestis colonization immediately after pathogenic challenge.

Repositories


GEO

GSE101653

BioProject

PRJNA395085

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Contact


Aarti Gautam