Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 11
Release date: Nov 1 2018
Last update date: Nov 2 2018
Access: Public
Diseases: Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Nervous System Diseases, Machado-Joseph Disease
Genes: SOX2, MYC, ATXN3
Taxon: Homo sapiens
Dataset link Blood-derived stable induced neural stem cells: Preservation of age-related DNA methylation patterns and applicability to disease modeling

Experimental Protocol


To study the relationship between blood-derived iNSCs with their parental blood cells and human pluripotent stem cell (hPSC)-derived conterparts, we selected 2 adult peripheral blood cell-derived iNSC (PB-iNSC) lines, 3 neonatal cord blood cell-derived iNSC (CB-iNSC) lines, 2 hPSC-derived small molecule-induced neural progenitor cell (smNPC) lines, 2 hPSC-derived long-term neuroepithelium stem cell (lt-NES) lines, 1 adult peripheral blood cell sample, 1 neonatal cord blood cell sample. We analyzed their global gene expression profiles via HumanHT-12 v4 Expression BeadChip Kit.

Repositories


GEO

GSE90129

BioProject

PRJNA354459

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Contact


Qiong Lin