ChIP-chip from pregnant female mouse pituitary with POU1F1 (PIT-1)

POU1F1 regulates, in the pituitary, the development of the prolactin-, growth hormone- and thyrotropin ß-expressing lineages and the expression of these hormone in the mature pituitary through the direct regulation of their promoters. Besides these functions, POU1F1 is also involved in other cellular processes in the pituitary, such as cell division and survival, but the genomic targets involved in these actions are not known. The present ChIP-chip study identified a large number of hitherto unknown potential direct targets that might be involved in these actions, such as Tcf4, Lmo4, Pax6, Trp53 etc.

Dataset features

Information

Specifications

Application:	ChIP-on-chip analysis
Number of samples:	6
Release date:	Oct 29 2011
Last update date:	Jul 31 2012
Access:	Public
Genes:	YND1, POU1F1, GH1, TCF4, LMO4, PAX6, TP53
Taxon:	Mus musculus
Dataset link	ChIP-chip from pregnant female mouse pituitary with POU1F1 (PIT-1)

Experimental Protocol

ChIP-chip was done from pregnant female mouse (C57Bl/6J) pituitary (3 pools of 12 pituitary anterior lobes, corresponding to three biological replicates) with POU1F1 (PIT-1)

Repositories

GEO

GSE33318

ArrayExpress

E-GEOD-33318

BioProject

PRJNA149305

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Contact

Jean-Paul Herman