Computational protocol: Macrophage migration inhibitory factor (MIF) modulates trophic signaling through interaction with serine protease HTRA1

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Protocol publication

[…] To determine hypothetical MIF–HTRA1 binding sites, the program Patchdock (Beta 1.3 Version) was used to identify molecular docking. The protein data bank (PDB) files for MIF (1ca7) and HTRA1 (2joa and 3num) were used for modeling. The Patchdock results were refined using the FireDock software [, ]. […]

Pipeline specifications

Software tools PatchDock, FireDock
Application Protein interaction analysis
Diseases Neoplasms, Neurodegenerative Diseases