Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 18
Release date: Sep 1 2006
Last update date: Aug 28 2018
Access: Public
Diseases: Neoplasms
Dataset link Gene Expression Biomarkers for Predicting Lung Tumors in Two-Year Rodent Bioassays

Experimental Protocol


Five week old female B6C3F1 mice were exposed for 13 weeks to the following treatments: 1) 1,5-Naphthalenediamine, CAS No. 2243-62-1, feed, 2000 ppm, positive lung carcinogen; 2) 2,3-Benzofuran, CAS No. 271-89-6, gavage, 240 mg/kg, positive lung carcinogen; 3) N-(1-naphthyl)ethylenediamine dihydrochloride, CAS No. 1465-25-4, feed, 2000 ppm, negative lung carcinogen; 4) Pentachloronitrobenzene, CAS No. 82-68-8, feed, 8187 ppm, negative lung carcinogen; 5) Feed control; 6) Corn oil gavage control. Feed animals were exposed 7 days/week and gavage animals were exposed 5 days/week (5 ml/kg). Microarray analysis was performed on the lungs of three mice per treatment group.

Repositories


GEO

GSE5127

ArrayExpress

E-GEOD-5127

BioProject

PRJNA96629

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Contact


Russell Thomas
Russell Scott Thomas