|Application:||Gene expression microarray analysis|
|Number of samples:||3|
|Release date:||Oct 22 2016|
|Last update date:||Aug 16 2018|
|Diseases:||Carcinoma, Non-Small-Cell Lung, Neoplasms|
|Dataset link||Overcoming acquired resistance to BIBW2992 in HCC827, a non-small cell lung cancer cell line by dasatinib|
Over a period of 3-4 months, BIBW2992-resistant cells were isolated in cell culture by maintenance of HCC827 cells in the presence of escalating concentrations of BIBW2992 up to 2 μM. Two cell lines, HCC827-BR1 and HCC827-BR2, were established based on individual clones. Total RNA of these HCC827, HCC827-BR1 and HCC827-BR2, were extracted for gene expression microarray analysis using Illumina HumanHT12 v3 BeadChip.
Shih Sheng Jiang