Dataset features

Specifications


Application: miRNA array analysis
Number of samples: 24
Release date: Dec 23 2016
Last update date: Mar 24 2017
Access: Public
Diseases: Arthritis, Rheumatoid
Dataset link Agilent Chip Data of the Post-Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Agilent, miRNA, batch 1)

Experimental Protocol


The experiment is designed as 5 arms: epidermal needle manipulation (AP/MEC), Methotrexate injection (MTX), Isofluorane anesthetic (ANE, used as anesthesia control) and placebo (PLA, used as control) on CIA induced rheumatoid arthritis (RA) rats, as well as the normal rats (NORA, healthy control). Whole blood sampling was carried out before any therapy in RA (RA_T0) and NORA (NORA_T0) groups, and in the other groups (AP/MEC, MTX,ANE, PLA and NORA) at 1 hour and 34 days after the start of therapeutic treatments. Finally, 24 total RNA samples (two replicates for each sampling) extracted from 24 blood samples (Peripheral blood mononuclear cells, PBMC ) were analyzed using Agilent technology (Agilent-031189 unrestricted_Rat_miRNA_v16.0_Microarray).

Repositories


GEO

GSE58458

BioProject

PRJNA252675

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Contact


Christine Nardini

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