A database of functional and regulatory elements of cancer-associated fusion events. FARE-CAFE is a database with the combination of the cancer related chromosomal translation events, fusion genes, domains, domain-domain interactions (DDI), protein-protein interactions (PPI), transcription factors(TF) and miRNAs collectively with the consequent experimental information. The significance of this database is currently, there is no database endow with fusion proteins role in terms of PPI and DDI in oncogenesis. This database provides detailed information about cancer related fusion genes regulatory (TFs and their target miRNA) and functional elements (domains, DDIs, PPIs). FARE-CAFE database will helpful to demonstrate clear understanding on molecular mechanism of cancer progression and ultimately pilot to the expansion of novel therapeutic approaches.
Department of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan
FARE-CAFE funding source(s)
Ministry of Science and Technology (MOST) of the Republic of China, Taiwan; Grant of MOST 102-2632-E-468-001-MY3; Asia University (103-asia-06) and China Medical University (CMU103-ASIA-21); Grant of MOST 102-2632-B-039-001-MY3; Grant of MOST 104-2221-E-150-039; National Formosa University (EN103B-1005); China Medical University (CMU103-ASIA-21)