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FastTree | Computing large minimum evolution trees with profiles instead of a distance matrix

Online

Constructs large phylogenies and estimates their reliability. FastTree uses nearest-neighbor interchanges (NNIs), the minimum-evolution criterion, minimum-evolution subtree-pruning-regrafting (SPRs) and maximumlikelihood NNIs to improve the tree. It uses heuristics to restrict the search for better trees and estimates a rate of evolution for each site. For large alignments, FastTree is 100-1,000 times faster than PhyML 3.0 or RAxML 7.

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FastTree classification

FastTree specifications

Unique identifier:
OMICS_14703
Interface:
Command line interface
Input format:
FASTA, PHYLIP
Operating system:
Unix/Linux, Mac OS, Windows
Computer skills:
Advanced
Stability:
Stable
Maintained:
Yes
Software type:
Package/Module
Restrictions to use:
None
Output format:
NEWICK
Programming languages:
C
Version:
2.1.9
Source code URL:
http://microbesonline.org/fasttree/FastTree.c

FastTree distribution

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FastTree support

Documentation

Maintainer

  • Morgan Price <>

Credits

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Publications

Institution(s)

Physical Biosciences Division, Lawrence Berkeley National Lab, Berkeley, CA, USA; Virtual Institute of Microbial Stress and Survival, Lawrence Berkeley National Lab, Berkeley, CA, USA; Department of Bioengineering, University of California, Berkeley, CA, USA

Funding source(s)

This work was supported by a grant from the US Department of Energy Genomics: GTL program (DE-AC02-05CH11231).

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