Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 12
Release date: Sep 9 2013
Last update date: Feb 2 2018
Access: Public
Diseases: Friedreich Ataxia, Neural Tube Defects
Chemicals: Folic Acid
Dataset link Maternal folic acid supplementation alters gene expression in the offspring brain

Experimental Protocol


C57BL/6J female mice were separated into two groups of ten mice and supplemented with a custom diet. One week prior to mating the low-dose group of female mice were fed a custom AIN-93G amino acid–based diet (Research Diet, Inc. New-Brunswick, NJ), with FA at 0.4 mg/kg, while the high-dose group received FA at 4 mg/kg diet. Tissues from the cerebral hemisphere of three independent pups of same gender were pooled together. A total of three microarray gene expression studies have been performed (0.4mg/kg or 4mg/kg both male and female) and the mean was used for comparison.

Repositories


GEO

GSE45607

ArrayExpress

E-GEOD-45607

BioProject

PRJNA195394

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Contact


Mohammed Junaid
Mohammed A. Junaid

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