Computational protocol: Sp6 and Sp8 Transcription Factors Control AER Formation and Dorsal Ventral Patterning in Limb Development

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Protocol publication

[…] Conservation of En1, Sp6 and Sp8 loci between mouse, human, opossum, chicken and zebrafish was determined using pairwise alignment software (mVista browser, Conserved noncoding regions were further analyzed for potential transcription factor binding sites using AliBaba 2.1 ( and Sequencher 4.8 (Gene Codes Inc.) informatic software. […]

Pipeline specifications

Software tools mVISTA, AliBaba, Sequencher
Application Nucleotide sequence alignment
Organisms Mus musculus
Diseases Abnormalities, Drug-Induced, Syndactyly