FBAT specifications

Information


Unique identifier OMICS_07500
Name Family Based Association Test
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Computer skills Advanced
Stability Stable
Maintained No

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FBAT articles

FBAT citations

 (7)
2016
PMCID: 4981730

[…] association test, and three genetic models (additive, dominant and recessive) were assumed for each snp analysis.25 to assess the effect of genetic variants on the trait value, a univariate family-based association test was performed for each allele. this test provides a z-statistic with its corresponding p-value. in the present study, a positive z-statistic for an allele or a haplotype […]

2013
PMCID: 3612041

[…] unaffected’ analyses). family-based association testing of allele transmission from parents to only affected offsprings was also performed (i.e., ‘affecteds only’ analyses). the hbat procedure in fbat was used to estimate haplotype frequencies and perform haplotype-specific and global tests of association. p-values <8.33×10−3 (0.05/6) were considered statistically significant., a total […]

2012
PMCID: 3485007

[…] of ld were analysed in haploview 4.2 [30]. as confirmation, association analyses were also undertaken using a conventional transmission disequilibrium test in the family-based association test (fbat) [31]., following quality control checks (see methods), illumina 660w quad beadchip genome-wide data was available for 535,544 genotyped snps (2,524,817 after imputation) in 416 om cases […]

2009
PMCID: 2700850

[…] bonferroni correction., the association analyses of the nine interesting snps (see details in the results section) in the fhs sample were performed in the similar way as for the aa sample, using the fbat program to examine association of the snps with smoking status (29)., we performed genome-wide genotypic association analyses for smoking status (adjusted for age and sex) and identified […]

2008
PMCID: 2525650

[…] were performed assuming additive, dominant, and recessive genetic models. in both cohorts, snps and haplotypes were tested for association with asthma and allergy-related phenotypes using the family-based association test statistic implemented in pbat version v3.2 [22]. consistent with our previous work, all analyses of quantitative phenotypes were adjusted for age and gender. results […]

FBAT institution(s)
Department of Biostatistics, Harvard University, Boston, MA, USA; Department of Biostatistics, Columbia University, New York, NY, USA
FBAT funding source(s)
Supported by FBAT (Family Based Association Tests) grant.

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