FBAT pipeline

FBAT specifications


Unique identifier OMICS_07500
Alternative name Family Based Association Test
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Computer skills Advanced
Stability No
Maintained No


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Publications for Family Based Association Test

FBAT IN pipelines

PMCID: 4981730
PMID: 27011258
DOI: 10.1038/jhh.2016.5

[…] association test, and three genetic models (additive, dominant and recessive) were assumed for each snp analysis.25 to assess the effect of genetic variants on the trait value, a univariate family-based association test was performed for each allele. this test provides a z-statistic with its corresponding p-value. in the present study, a positive z-statistic for an allele or a haplotype […]

PMCID: 4592257
PMID: 26430897
DOI: 10.1371/journal.pone.0139716

[…] option in the solar package. we conducted genome-wide family-based association analysis using the additive model to investigate genetic regions that might influence pulmonary function using fbat software version 2.0.3 [27]., we compared the results of the gendiscan study with data from the korea healthy twin study. the healthy twin study is an ongoing cohort study of twins […]

PMCID: 3612041
PMID: 23555951
DOI: 10.1371/journal.pone.0060301

[…] unaffected’ analyses). family-based association testing of allele transmission from parents to only affected offsprings was also performed (i.e., ‘affecteds only’ analyses). the hbat procedure in fbat was used to estimate haplotype frequencies and perform haplotype-specific and global tests of association. p-values <8.33×10−3 (0.05/6) were considered statistically significant., a total […]

PMCID: 3535370
PMID: 23064873
DOI: 10.1007/s00439-012-1229-4

[…] was performed to test association of the g84e mutation and other snps with prostate cancer by assessing over-transmission of alleles from parents to affected offspring using the computer program fbat (xu et al. 2002). empirical variance test statistics were used to account for the correlation of transmitted alleles among multiple affected individuals in the same family., haplotypes […]

PMCID: 3065289
PMID: 21364586
DOI: 10.1038/bjc.2011.61

[…] work at the institute of cancer research was supported by grants from cancer research uk (c1298/a8780 and c1298/a8362)., web addressesthe urls for data/software presented herein are as follows:, fbat: http://www.biostat.harvard.edu/~fbat/, primer 3: http://primer3.sourceforge.net/, r: http://cran.r-project.org/, ncbi dbsnp: http://www.ncbi.nlm.nih.gov/, online mendelian inheritance in man […]

FBAT institution(s)
Department of Biostatistics, Harvard University, Boston, MA, USA; Department of Biostatistics, Columbia University, New York, NY, USA
FBAT funding source(s)
Supported by FBAT (Family Based Association Tests) grant.

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