Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 139
Release date: Feb 8 2017
Last update date: Oct 24 2018
Access: Public
Diseases: Colorectal Neoplasms
Dataset link Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome

Experimental Protocol


H3K27ac profiles in 28 CRC cell lines, 4 primary CRC specimens, and 4 normal colon crypt samples; H3K4me1 profiles in 27 CRC cell lines, 4 primary CRCs, and 4 crypt samples; H3K27me3 profiles in 1 CRC cell line and 1 crypt sample; DNase hypersensitivity site profiles in 3 CRC cell lines and 3 crypt samples; and associated input DNA. Gene expression profiles for 6 CRC cell lines without treatment and at 4 time points of treatments with JQ1.

Repositories


GEO

GSE77737

ENA

SRP069828

BioProject

PRJNA311329

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Contact


Peter Scacheri

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